Fig. 2
From: Cocaine-induced sensitization and glutamate plasticity in the nucleus accumbens core: effects of sex
Effects of repeated systemic cocaine and subsequent withdrawal on calcium-permeable AMPAR (CP-AMPAR) mediated transmission. Time course showing effects of bath application of CP-AMPAR antagonist Naspm on eEPSC amplitude recordings in A males and B females. C Percent reduction in eEPSC amplitude following Naspm. Naspm produced similar decrease in eEPSC amplitude in both sexes, regardless of treatment (average of the last two minutes of drug wash on) Two-way ANOVA no effect of treatment F(1,32) = 0.68, p = 0.42; no effect of sex F(1,32) = 0.86, p = 0.36. D Example traces in males and females. E Cartoon depiction of where recordings were made within the slice (shaded region)