Fig. 4

Myeloid cells (CD11b⁺) are upregulated in different AT depots depending on sex. A CD11b⁺ cells are increasing with AS in male mice, while they are decreasing in female mice. B In male mice CD11b⁺ cells are not affected by DIO. But in female mice DIO upregulates them at all AS. (n = 6/♂ AS1 HFD scAT, AS3 HFD vAT, ♀ AS1 HFD, LFD vAT; n = 5/♂ AS1 HFD vAT, AS2 HFD, LFD scAT, AS3 HFD scAT, LFD vAT ♀ AS1 LFD scAT, AS2 HFD, LFD, AS3 HFD, LFD; n = 4/♂ AS2 LFD vAT, AS3 LFD scAT; n = 3/♂ AS1 LFD vAT); p ≤ 0.05*, p ≤ 0.005**, p ≤ 0.001***