Fig. 5

Only in male mice, CD11b⁺ cells inflammasome activation is upregulated with DIO. A Myeloid cells (CD11b⁺) have an upregulated inflammasome activation due to DIO in male mice. In Th cells (B, CD3⁺CD4⁺), B cells (C, CD19⁺) and CD8⁺ T cells (D) changes in inflammasome activation are not clearly linked to adiposity. (n = 3–6/group, see Figs. 2 + 4); p ≤ 0.05*, p ≤ 0.005**, p ≤ 0.001***